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Road Trip with RVshare Fort Myers to Key West

Your Trip At a Glance

  • Trip Length: 5 hours, 39 minutes
  • Mileage: 276 miles
  • Fun fact: Key lime pie, which is Florida's official state pie, supposedly originated in Key West.

Traveling from Fort Myers to Key West allows you to leave the Florida mainland and see the stunning islands scattered around the coast. During your trip, you'll have plenty of opportunities to stay in an RV campground, check out national parks and visit tourist destinations. Make sure you try the famous key limes!

Road Trip Planner: Stops Along Your Route

Fort Myers to Key West Road Trip Section Image

Once you hit the road in your RV, you'll pass through cities, small towns and suburban areas until you reach US-1, which crosses the Florida Keys. If you're up for a little adventure, you can veer off the path to check out Miami or nearby state parks.

Miami, Florida

Miami is one of the top destinations for people who love relaxing beaches, tropical restaurants and exciting nightlife. If you want to get away from the crowds, Miami has numerous campgrounds, hiking trails and nature areas. Grab a souvenir at one of Miami's bustling shopping centers, then check out the events, concerts and festivals that the city hosts year-round.

RV Info & Tips:

Campgrounds: Encore Miami Everglades (swimming pool, general store), Palm Garden RV Park (full hookups, concrete patios)

How Long to Stay: Consider staying for a day or two so that you can see most of the attractions.

Gear & Prep: Bring your bags, sunscreen, sunglasses, bottled water and comfortable, loose-fitting clothes.

Anhinga Trail

Take a short break with Anhinga Trail. This trail is less than a mile long and takes you through a sawgrass marsh where you'll have plenty of opportunities to see wildlife, such as alligators, turtles and various bird species. If you enjoy wildlife photography, this is your chance to get the perfect shot. While you're there, check out the Royal Palm Visitor Center at the head of the trail.

RV Info & Tips:

Roads: When you reach Florida City, get on US-9336 and keep driving west until you reach the entrance.

How Long to Stay: Most people stay for a few hours or less.

Gear & Prep: Bring your boots, hats, sunscreen, comfortable clothing and other walking gear.

Fruit & Spice Park

Fruit & Spice Park is home to over 500 varieties of fruits, vegetables, spices, nuts and herbs, including 150 different mango varieties. You'll get the chance to try various fruits during your trip, so make sure you bring your appetite. Take advantage of the free walking tour, or schedule a Tasting or Garden Tram tour for a more immersive experience.

RV Info & Tips:

Roads: Take US-997 south, then turn right on Coconut Palm Drive and keep driving until you reach the entrance.

How Long to Stay: Most tours take less than a few hours.

Gear & Prep: You'll spend a lot of time outdoors, so bring your hats, sunglasses, sunscreen and bug spray.

Top RV Rentals Near Fort Myers, Florida

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Pro Tips to Make the Most of Your Trip

Getting to Key West can be tricky, so it's important to plan ahead. You'll need to stock your RV with seasonal gear, plan ahead for fuel stops, and choose a route that maximizes your fun. If you're not comfortable driving over large stretches of water, you might want to try a few mainland trips before you tackle this one.

Take the Scenic Route Out

If you want to stop at Miami on the way, take I-75 until you reach US-41, then keep driving straight instead of turning at US-997. Miami sits right on the coast, with highways connecting you to the local islands. When you're done exploring, get on US-997 to continue your journey.

Alternate Route Options

This route adds some mileage to your trip, but you can get closer to Miami by staying on I-75 until you hit Miami Lakes. If you have some extra time, you could also take US-80 and US-27, passing through LaBelle, Clewiston, South Bay and Okeelanta, until you hit I-75 near Miramar.

Fuel & Supplies Along the Way

You'll find gas stations stocked with fuel and supplies throughout your route, including Shell, Mobil, RaceTrac, Murphy USA and other major brands. Most gas stations sit near intersections and suburban areas. If you need fuel about midway through your trip, Miami has dozens of gas stations, grocery stores and rest stops for your convenience.

RV Route Logistics

• RV-friendly campgrounds: Most campgrounds are located in Key West and nearby islands. However, if you have to stop early, you'll find a few RV-friendly sites along US-1. You could also stay overnight in Miami before heading down to the Keys.

• Ideal duration: Consider staying 2-3 days so that you can travel to nearby islands and visit the beaches, stores and nature areas.

• Gas stations: Once you hit the Florida Keys, you'll drive across large sections of ocean without gas stations, so make sure you fuel up when you have the chance.

• RVing along this route: Most of this route stays on the interstate and one or two major highways, making it ideal for RV travelers. Just keep in mind that you'll drive over large patches of ocean once you reach the Florida Keys.

• Seasonality: Key West's tropical climate is fairly hot and humid in the summer. If you can tolerate the heat, this is the best time to check out local events, festivals and live music. However, if you prefer cooler temperatures and fewer crowds, consider visiting Key West during the winter months.

Traveling from Fort Myers to Key West is a great way to visit famous cities and appreciate Florida's natural landscape. When you're ready to start your journey, rent an RV in Fort Myers or Key West and see where the road takes you.

Frequently Asked Questions

How do I plan an RV road trip from Fort Myers to Key West?

To plan an RV road trip from Fort Myers to Key West, start by mapping your route using Google Maps or a trip planner that supports RV navigation. Consider road types, fuel stops, campgrounds, and attractions along the way. Our RV rental specialists can help you choose the best vehicle and route based on your travel dates and preferences.

What type of RV should I rent for my trip?

The ideal RV depends on your travel style, group size, and destination. For couples, a camper van or Class B RV offers flexibility and easy driving. Families often prefer Class C motorhomes for more space and amenities. If you’re staying longer or need extra comfort, a Class A RV might be your best choice. Learn more about the different RV classes.

How much does it cost to rent an RV for a road trip?

RV rental prices vary based on vehicle size, rental duration, season, and mileage. On average, RV rentals range from $100–$300 per night, with discounts for weekly or monthly bookings. We also offer one-way rentals if you’re traveling from Fort Myers to Key West without returning to the starting point.

Can I pick up my RV in one city and drop it off in another?

Yes! Many travelers love our one-way RV rental option. If the inventory is available for your route, you can pick up your RV in one location and drop it off in another, which is perfect for cross-country adventures or long-distance road trips.

What should I pack for an RV trip?

Pack essentials like bedding, toiletries, cooking supplies, and outdoor gear. Most of our RVs come equipped with kitchenware and basic amenities. Don’t forget to bring a first-aid kit, maps, and camping chairs for your outdoor setup. Keep this packing list handy to ensure you don’t leave anything behind!

Do I need a special license to drive an RV?

A standard driver’s license is all you need to rent and drive an RV. Keep in mind that you must be 25 to rent an RV.

Where can I park or stay overnight during my road trip?

You can stay at RV parks, national park campgrounds, or designated boondocking areas. Our team can recommend safe and scenic stops along your route from Fort Myers to Key West. Be sure to reserve campgrounds in advance during peak travel seasons.

How do I handle fuel and hookups during my trip?

Most RVshare RVs are equipped for electric, water, and sewer hookups at most campgrounds. Keep track of your fuel stops and learn how to connect utilities before you hit the road. We provide a full orientation before departure to make setup easy.

Is insurance included in my RV rental?

Yes, basic insurance coverage is included with every rental. You can also purchase additional protection plans for peace of mind during your journey. We’ll explain all coverage options when you book your RV.

Can I travel with pets in my RV rental?

Absolutely! Many of our RVs are pet-friendly, so your furry friends can enjoy the adventure too. Use the filters to search for RVs that welcome pets on board.

What are the best road trip routes for RV travelers?

Popular RV routes include scenic coastal drives, national park loops, and cross-country highways. For beginners, you may want to try a long weekend trip where you don’t have to drive quite as far. Just remember to follow the 3-3-3 rule of RVing!